Takeda & Janssen : About Agreement Reached to Co-market R113675 (Galantamine Hydrobromide), a Treatment for Alzheimer’s Disease

April 1, 2010 --- Takeda Pharmaceutical Company Limited (“Takeda”) announced that it has signed an agreement dated March 31, 2010 with JANSSEN PHARMACEUTICAL K.K. (Head Office: Tokyo, President: Toon Overstijns, hereinafter called “Janssen Pharma”) and Janssen Pharmaceutica N.V. (Head Office: Belgium, Managing Director: Tom Heyman) regarding co-marketing in Japan of galantamine (R113675), which is a drug for Alzheimer's Disease and chemically known as galantamine hydrobromide (hereinafter called “galantamine”).


Following the development of galantamine by Janssen Pharmaceutica, for the treatment of Alzheimer’s Disease in Japan, Janssen Pharma submitted an application for approval to the Ministry of Health, Labor and Welfare in February 2010.


Once approved, Takeda and Janssen Pharma will co-market galantamine under the same brand name... Takeda's Press Release - JANSSEN PHARMACEUTICAL K.K.'s Press Release [Japanese] -

Antigenics : Expansion of its QS-21 License Agreement

September 21, 2009 — Antigenics Inc. (NASDAQ: AGEN) announced that the company has signed an amended and restated license agreement for the use of the QS-21 adjuvant in a vaccine under development by JANSSEN Alzheimer Immunotherapy, a company which has acquired substantially all of the assets and rights of Elan related to its Alzheimer's Immunotherapy Program (AIP).


“Alzheimer's disease is the sixth-leading cause of death in the United States, and the incidence of this disease is expected to rise globally.” said Garo H. Armen, PhD, chairman and CEO of Antigenics. “Today's announcement underscores the importance of QS-21, which is being tested in multiple indications by our licensees, including four Phase 3 programs in lung cancer, malaria, melanoma and an undisclosed infectious disease. QS-21 is enabling a new generation of vaccines to be developed and is expected to become a significant contributor to Antigenics' future royalty income, with the first vaccine potentially on the market by 2011.”... Antigenics' Press Release -