GlaxoSmithKline and AFFiRiS : exclusive licence and option agreement for therapeutic Alzheimer’s disease candidate vaccines

23 October 2008 - GlaxoSmithKline Biologicals S.A. (GSK) and AFFiRiS GmbH announced the execution of a collaboration agreement granting GSK exclusive rights to AFFiRiS’s Alzheimer’s disease vaccine programmes, aimed at treating Alzheimer’s by targeting beta-amyloid.

As part of the agreement, GSK is acquiring exclusive rights to develop and commercialise two Alzheimer’s disease vaccine candidates that are based on AFFiRiS AFFiTOPE technology and are currently in Phase I clinical development. AFFiRiS is also granting GSK an exclusive option to develop and commercialise alternative Alzheimer’s disease vaccine candidates which are in preclinical development... GlaxoSmithKline's Press Release - [PDF] AFFiRiS' Press Release -

Affiris, European Patent for Alzheimer’s Vaccine

November 2007. Affiris GmbH has been granted a Europe-wide patent for key elements of its Alzheimer’s vaccine. As a result, the company has exclusive rights of use to the peptide sequences for an innovative approach to vaccine development. The tolerability of the first Affiris vaccine, AFFITOPE AD01, is currently being tested as part of a phase I clinical trial... [PDF] Affiris' Press Release -